Lewiston is located in Androscoggin County and about 35 miles (56 km) north of Portland, Maine.
The Sun Journal, citing a Lewiston police spokesperson, reported shots fired at three separate businesses: SpareTime Recreation, Schemenzie’s Bar & Grill restaurant, and a Walmart distribution center.
A US official in Washington said President Joe Biden has been briefed and will continue to receive updates.
Maine Governor Janet Mills said in a statement that she had been briefed on the situation.