In contrast, Wolves had already lost Lopetegui six days earlier due to a lack of funds in the transfer market.
O’Neill replaced the Spaniard after he was appointed to repeat his heroics in keeping Bournemouth in the Premier League last season.
The Wolves club did not appear to be in trouble as they took control of the game, but they suffered from a lack of lead going forward.
Pablo Sarabia and Mathias Cunha created the best chances of the first half just before the post.
At the start of the second round, Cunha came even closer. Brazil should have scored when he hit the outside of the post with the goal gaping.
Wolves’ budget has been limited by a £44million obligation to sign Cunha from Atletico Madrid this summer.